Ph.d.-stillinger – Københavns Universitet

Videresend til en ven Resize Print Bookmark and Share

Jobportal DK > Ph.d.-stillinger

PhD Fellowship in Intrinsic Antibiotic Resistance

Department of Veterinary and Animal Sciences  
Faculty of Health and Medical Sciences  
University of Copenhagen  
 
Department of Veterinary and Animal Sciences (IVH), Faculty of Health and Medical Sciences at University of Copenhagen is offering a PhD Fellowship in Biology of Antibiotic Resistance to commence on 1 February 2018 or as soon as possible thereafter. The position is limited to three years.
 
Information about the Department can be found at http://ivh.ku.dk/english/.
 
Aim
Bacteria show a natural variation in resistance levels towards antibiotics. The aims of this PhD project are to 1) determine the genes that contribute to this natural resistome of the human pathogen, Staphylococcus aureus, 2) investigate the molecular mechanisms behind resistance and 3) search for compounds that may target such resistance mechanisms.
 
Background
Antibiotic resistance is one of the great challenges to human health and at IVH we have for many years studied antibiotic resistance in bacteria causing disease in humans and animals. The position will be based at Hanne Ingmer’s group that focuses on studies of antibiotic resistance, alternatives to antibiotics and transfer of resistance genes and it will address how biological variation and gene expression influence antibiotic resistance. As part of Cartnet, an EU funded training network for PhD students involving students from other disciplines (chemists, biologists), the successful candidate should be prepared for scientific stays and training events at other institutions involved in Cartnet. The overall aim of CARTNET is to train young researchers in Europe to address serious and global problems of antibiotic resistance.
 
Project description
The candidate will be determining the contribution of the intrinsic bacterial resistome to antibiotic resistance in the serious human pathogen, Staphylococcus aureus. Methicillin resistance in S. aureus (the MRSAs) and resistance to other antibiotics is an increasing health problem and the PhD will address how bacterial core genes (defined as the intrinsic resistome) affect the development and stability of antibiotic resistance. The project will involve genetic manipulations including high throughput mutation analysis of S. aureus and screenings of large mutant libraries. Identified resistance genes will be characterised and compounds targeting will be sought from natural and synthetic cources.
 
Project organisation
The project has a duration of 3 years. The PhD fellow will be associated to the MSCA-ITN-2017 training network CARTNET, and the fellow will be enrolled in the PhD programme Molecular Bacteriology and Infection at the Faculty of Health and Medical Sciences, University of Copenhagen. We offer the opportunity to work in a state-of-the-art, highly innovative and scientifically stimulating environment with ambitious colleagues, excellent training opportunities, both personally and professionally and the opportunity to contribute with new knowledge to an exciting and fast-moving scientific field.
 
Principal supervisor
Professor Hanne Ingmer
Email: hi@sund.ku.dk
Direct Phone: (+45) 2215 9518
 
Required qualifications
  • MSc in a biological science, molecular biology, biotechnology, medicine or other equivalent degree
  • A special interest and competencies within microbiology of human bacterial pathogens and antibiotic resistance
  • Excellent molecular biology skills
  • High level of motivation, responsibility and flexibility
  • Highly enthusiastic, ambitious and team-oriented personality
  • Excellent communication skills in English (written and oral)
Preferred qualifications
  • Experience with antibiotic resistance
  • Experience with whole genome sequencing and bioinformatics
General Job description
Your key tasks as a PhD fellow at Faculty of Health and Medical Sciences (SUND) are to:  
  • Manage, carry through and conclude your research projects, from experiments to analyses of samples
  • Actively participate in PhD courses
  • Write scientific articles and finalise your PhD thesis
  • Participate in international congresses
  • Conduct research stays and participate in training events at institutions involved in Cartnet
  • Teach and disseminate your research
We offer
  • A highly important research topic, aiming to address one of the major global challenges to human health
  • A scientific environment with highly dedicated colleagues from wide academic backgrounds
  • An international work atmosphere with a large proportion of non-Danish co-workers
  • A research environment that strives to provide strong impact both in science and on human health
Key criteria for the assessment of candidates
  • The grade point average achieved in relevant University degrees
  • Professional qualifications relevant to the PhD programme
  • Previous publications (if any)
  • Relevant work experience
  • Other professional activities
  • Language skills, including English
  • The successful candidate is also required to be resourceful and to possess good interpersonal skills
  • At the 1st day of employment, it is required that the candidates have not previously been awarded a PhD (or equivalent) and must be in the first four years of their research careers. Furthermore, the candidates must not have worked or studied in Denmark for more than 12 months in the three years prior to the start of the employment
Formal requirements
The position is available for a 3-year period for applicants holding a relevant master´s degree. The successful candidate will be requested to formally apply for enrolment as a PhD fellow at the Graduate School of Health and Medical Sciences. Employment as a PhD fellow will be conditional on successful enrolment in the PhD programme according to the rules stipulated in “Bekendtgørelse nr. 18 af 14. januar 2008 om ph.d.-graden.“
 
Terms of employment
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organisations. Depending on seniority, the monthly salary begins around DKK 26.073 (approx. 3.499 EUR) plus pension. The position is covered by the Job Structure for Academic Staff at Universities (2013).
 
Questions
For further information about the position please contact Professor Hanne Ingmer, email hi@sund.ku.dk. For any administrative queries please contact HR Officer Marie-Louise Rosenlund, email mlr@sund.ku.dk.
 
Foreign applicants may find the following link useful: www.ism.ku.dk (International Staff Mobility).
 
General information about PhD programmes at the Faculty of Health and Medical Sciences is available on the Graduate School’s website http://healthsciences.ku.dk/phd/.
 
Application procedure
The application must be submitted in English, by clicking on “Apply online” below and must include the following:  
  • Cover letter detailing your motivation and background for applying for the specific PhD project
  • CV
  • Diploma and detailed transcripts of records
  • Other information for consideration, e.g. list of publications (if any), peer reviewed and other
  • Personal recommendations (if any)
  • A maximum of 3 relevant scientific works which the applicant wishes to be included in the assessment (if any)
The deadline for applications is 23 December 2017 at 23:59. Any applications received after this time or incomplete will not be considered.
 
Receipts of the applications will be acknowledged, and the applicant will be kept continuously informed of the progress of the application.
 
The further process
Shortlist: After the expiry of the deadline for applications, the authorised recruitment manager selects applicants for assessment on the advice of the Appointment Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk.
 
Assessment: The selected applications will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritised assessment of the academic qualifications and experience with respect to the mentioned area of research, techniques, skills and other requirements listed in the advertisement.
 
Please note that the applicant will be contacted if the assessment committee requires further documentation.
 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.
 
The project is part of the Marie Curie ETN training network (CARTNET) and will involve secondments at other sites involved in the network. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 765147.
 
SØG STILLINGEN

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt

Hanne Ingmer
E-mail: hi@sund.ku.dk

Info

Ansøgningsfrist: 23-12-2017
Ansættelsesdato: 01-02-2018
Arbejdstid: Fuldtid
Afdeling/Sted: Institut for Veterinær- og Husdyrvidenskab

Søg i stillinger