PhD position in Structural Biology available within TAMiR - Targeting AMR by inhibition of bacterial stress responses

A PhD position in structural biology at the Structural Biology and NMR Laboratory, Department of Biology, Faculty of Science, University of Copenhagen, Denmark, is available from March 15th, 2020, or soon thereafter. The position is part of the newly funded consortium- TAMiR – that connects research groups in Copenhagen, Oslo and Trondheim in the aim of targeting antimicrobial resistance by inhibition of the bacterial stress responses. TAMiR is funded by the TROND MOHN foundation in Norway. The PhD student will also be affiliated with the REPIN Centre on Intrinsically Disordered Proteins (www.bio.ku.dk/repin).
 

PhD position
A 3-year PhD position will be available for the studies of disordered proteins interacting with large DNA clamps, such as proliferating cell nuclear antigens and the beta-clamp. The PhD student will apply a suite of biophysical techniques, with special focus on multidimensional, heteronuclear biomolecular NMR spectroscopy. Other techniques include ITC, MST, CD, stopped-flow kinetics as well as biochemical assays. The project will seek to promote the understanding of the role of flanking regions for discriminative binding, mapping mechanisms and specificity via kinetics and thermodynamics, as well as determining structures and ensembles. An exchange period in Trondheim is anticipated.

The position is available for a 3-year period and your key tasks as a PhD student at SCIENCE are:
•    To manage and carry through your research project
•    Attend PhD courses
•    Write scientific articles and your PhD thesis
•    Teach and disseminate your research
•    To stay at an external research institution for a few months, preferably abroad
•    Work for the department

Qualifications:
We are seeking a highly motivated applicant with an MSc degree in chemistry, biophysics, biochemistry or related fields with the following competences:

•    Protein expression and purification, including optimization of protocols
•    Structural biology
•    Good oral and written English competences

It will be highly advantageous to have one or more of the following qualifications:

•    Protein NMR spectroscopy, including set-up and spectral analyses (hands-on experience beyond course level)
•    Experience with biophysical techniques such as ITC, stopped-flow, CD or fluorescence spectroscopy or small angle X-ray scattering (hands-on experience beyond course level)
•    Publications in peer-reviewed scientific journals

Questions
For further information about the PhD position, please contact Professor Birthe B. Kragelund (bbk@bio.ku.dk).

Terms of employment 
The position is covered by the Memorandum on Job Structure for Academic Staff. 

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. 

The starting salary is currently at a minimum DKK 328.355 (approx. €43,750) including annual supplement (+ pension at a minimum DKK 53,360). Negotiation for salary supplement is possible.

Application Procedure
The application, in English, must be submitted electronically by clicking APPLY NOW below. 

Please include 
•    A 1-page cover letter explaining the applicant´s background, key competence in relation to the position and reasons for applying
•    A 1-page curriculum vitae 
•    Diploma and transcripts of records (BSc and MSc)
•    Contact details for 1-2 former employers or supervisors
•    Other information for consideration, e.g. list of publications (if any)

The deadline for applications is January 5th, 2020, 23:59 GMT +1. Applications received after the deadline for applications will not be considered. 

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee. Afterwards an assessment committee will be appointed to evaluate the selected applications. The applicants will be notified of the composition of the committee and the final selection of a successful candidate will be made by the Head of Department, based on the recommendations of the assessment committee and the interview committee. 
The main criterion for selection will be the research potential of the applicant and the above-mentioned skills. The successful candidate will then be requested to formally apply for enrolment as a PhD student at the PhD school of Science. You can read more about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

 General information about PhD programmes at SCIENCE is available at http://www.science.ku.dk/phd.

SØG STILLINGEN

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Info

Ansøgningsfrist: 05-01-2020
Ansættelsesdato: 15-03-2020
Arbejdstid: Fuldtid
Afdeling/Sted: Department of Biology

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