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Postdoctoral Fellow in Neurodegeneration

At Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences at University of Copenhagen a position as Postdoc in Neurodegeneration is available from 1 January 2018 or as soon as possible thereafter.  
 
Information about the Department can be found at http://ivh.ku.dk/english/.  
 
Background  
Within BrainStem, patient-specific neurons are derived from induced pluripotent stem cells obtained from skin fibroblasts to study Alzheimer’s diseases with the long-term aims of patient specific treatment and drug development http://brainstem.dk. Another line of research deals with canine cognitive disorder (CCD), resembling some aspects of human dementia. The Postdoc will work with both human and dog cellular models of dementia and validate the usefulness of the CCD dogs as demetia models in a cellular setting.  
 
Project description   
The project will include functional characterization of neurons and astrocytes derived from hiPSC and the generation of canine iPSC. Canine iPSC, after completed characterization and assessment of pluripotency status and genomic integrity, will be differentiated into astrocytes and neurons and compared in functional studies to the human counterparts.  
 
Selection criteria  
Essential criteria   
  • PhD in Animal Husbandry Science or similar  
  • Expertise and experience in human iPSC culture and generation, hands on experience with differentiation of hiPSC into neurons and astrocytes, engineering of 3D neural organoids and CRISPR/Cas9 mediated gene editing.  
  • Excellent in English both in writing and speech  
  • Good interpersonal skills and teamwork spirit   
Desirable criteria  
  • Pyrosequencing to assess the parent of origin of hiPSC  
  • Experience with animal ES culture such as mouse ES cells including in vitro fertilization   
Relationships  
  • The post holder will report to Poul Hyttel and Kristine Freude  
  • The post holder is expected to interact with staff at all levels, both internally and externally, regarding relevant research topics 
Employment conditions  
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organisations. The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.  
 
The gross basic salary range for Postdoctoral Fellows is DKK 32,332 to DKK 34,060 per month (level 6 to 8). To the basic salary, a supplement could be negotiated, dependent on the candidate’s experience and qualifications. The employer will pay an additional 17.1 % monthly contribution to pension.  
 
The position is time limited to a two-year period.  
 
Questions  
For further information about the position please contact Associate Professor Kristine Freude, e-mail kkf@sund.ku.dk or for any administrative queries, HR Officer Marie-Louise Rosenlund mlr@sund.ku.dk. 
 
Application  
Apply by clicking "Apply online" below. Please note that only online applications will be accepted.  
 
Applications - in English - must include:  
  • A letter of motivation (cover letter)  
  • Curriculum vitae  
  • List of publications  
  • Copy of diplomas/degree certificates   
The deadline for applications is 22 October 2017. Any applications received after this time or incomplete will not be considered.  
 
Receipts of the applications will be acknowledged, and the applicant will be kept continuously informed of the progress of the application.  
 
The further process  
Shortlist: After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether the expert assessment committee has passed their application for assessment. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk.  
 
Assessment: The selected applications will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the mentioned area of research, techniques, skills and other requirements listed in the advertisement.  
 
Please note that the applicant will be contacted if the assessment committee requires further documentation.  
 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.  
 
SØG STILLINGEN

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt

Kristine Freude
E-mail: kkf@sund.ku.dk

Info

Ansøgningsfrist: 22-10-2017
Ansættelsesdato: 01-01-2018
Arbejdstid: Fuldtid
Afdeling/Sted: Institut for Veterinær- og Husdyrvidenskab

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