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Three PhD Scholarships to Center for Translational Neuromedicine

Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, University of Copenhagen is looking for three highly motivated PhD fellows. The positions offer the opportunity to work in a collaborative multi-disciplinary team engaged in research in The Ocular and Brain Glymphatic System. It is also the title (acronym: GlymphEye) of Prof. Maiken Nedergaard’s Horizon 2020, ERC Advanced Grant, which is partly sponsoring two of the PhD positions. 
Description of the center and the research group 
Our center is part of the Faculty of Health and Medical Sciences of the University of Copenhagen and is located at the Panum Institute. We currently have 55 employees and students formed into two interacting groups: the Division of Glial Disease and Therapeutics and the Division of Cell and Gene Therapy. The Center comprises newly constructed laboratories with excellent facilities for neuroscience. 
The research focus of the Division of Glial Disease and Therapeutics is on the basic biology of glial cells in the central nervous system, specifically astrocytes, and their role in several neurological and neuropsychiatric diseases, including stroke, spinal cord injury, epilepsy, tremor, ALS, schizophrenia. Sleep disturbances and the sleep-wake regulation of astrocytic calcium signalling are other focus areas of the Division. Our research is aimed at defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction. 
For further information about the center/research group, please see:   
Description of the PhD projects 
The glymphatic system is a highly organized brain-wide mechanism by which fluid wastes are removed from the brain. The glymphatic system clears 65% of amyloid-beta from the normal adult brain. A rapidly evolving literature has implicated the glymphatic system in a number of neurological diseases, including Alzheimer disease, traumatic brain injury, depression, and the beneficial effects of exercise on brain function. Recent publications have suggested that an ocular glymphatic system exist. We are looking for three PhD candidates to embark on the following projects: 
PhD#1 will focus on the study of the ocular glymphatic system in vivo using several optical approaches, as well as imaging based on PET/CT/MRI 
PhD#2 will study the role of the ocular glymphatic system in glaucoma 
PhD#3 will establish the relationship between cortical astrocytic Ca2+ signaling and the glymphatic system 
Job description 
The key tasks as a PhD fellow at the CTN are to: 
Carry out and complete an independent research project under supervision. 
Write scientific articles and the PhD thesis on the grounds of the research project. 
Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points. 
Obtain experience with teaching and/or other types of dissemination related to the PhD project. 
Participate in national and international congresses and scientific meetings. 
We are looking for highly motivated and enthusiastic candidates with the following qualifications: 
Candidates for the PhD positions must hold a Master’s degree in biology or medicine. Previous training in neurobiology is highly beneficial. 
Accredited course in laboratory animal science. 
At least one year of competent laboratory experience enabling the candidate to execute independent laboratory work. 
Dedication to outlined research protocols is necessary. 
The successful candidate should be organized, self-motivated, result-oriented and capable of working independently in a collaborative setting. 
The successful candidate will possess strong written and oral (English) communication skills with the ability to readily learn new experimental techniques. Strong analytical, communication, organizational and computer skills are also required. 
Terms of employment 
The three successful candidates will be offered a full-time 3-year position. The positions are covered by the Memorandum on Job Structure for Academic Staff. 
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. 
How to apply 
Your application must be submitted electronically by clicking "APPLY NOW" below. The application must include: 
 - A clear indication of which PhD position you are applying for (PhD#1, 2 or 3). 
 - Curriculum vitae, incl. education, work/research experience, language skills and other skills relevant for the position. 
 - MSc diploma together with the transcript of university examinations. 
 - A motivation letter describing your research interests and reasons for applying to one of the three positions. It should contain prior examples illustrating your drive and abilities that would be pertinent to the position. 
 - A list of the publications (or manuscripts) that have been submitted or accepted for publication. 
 - The contact information of two to three referees. 
The deadline for applications is 31 January 2018. Further information about the center can be found at Inquiries about the positions can be made to Senior Advisor Louise Thers Nielsen:
Application procedure 
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointment Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him-/herself. You can read about the recruitment process at
CTN and the University of Copenhagen wish to reflect the diversity of society and thus welcome applications from all qualified candidates regardless of personal background. 

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Louise Thers Nielsen


Ansøgningsfrist: 31-01-2018
Ansættelsesdato: Start hurtigst muligt
Arbejdstid: Fuldtid
Afdeling/Sted: Center for Translational Neuromedicine

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