Post Doctoral Fellow for Mass Spectrometry-Based Proteomics Investigation of Cardiac Disease Mechanisms

Job Description

The Cardiac Proteomics and Systems Biology Group at Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, is seeking to employ a Post Doctoral fellow. The successful candidate will investigate spatial- and cell type-resolved proteomes of heart samples across cardiac diseases as starting point for further investigations of cardiac disease mechanisms. The research fellow will focus on mass spectrometry based proteomics investigations of human heart samples in combination with experimental studies in iPSC derived cardiomyocytes.

We are seeking a highly motivated scientist to join our team. Prior experience with mass spectrometry-based proteomics is required.

Qualification Requirements

• PhD in a relevant field
• Ambitious, creative, independent and self-driven
• Hands-on skills and expert knowledge in one or more of the following areas:
  • Experimental know-how of mass spectrometry-based proteomics (LC-MS/MS)
  • Analytical know-how of mass spectrometry data analysis
  • Experimental know-how of various types of sample preparations (such as proteomics, PTMomics, clinical proteomics, spatial- or single cell proteomics, secretomics, interactomics using high-resolution mass spectrometry).
  • Experience in quantitative proteomics approaches
• Experience in cardiac biology is an advantage.
• Good communication skills in English, both oral and written.
• Willingness to engage in teamwork
• At least one first author publication in a relevant field

The preferred applicant should have an excellent academic track record, solid research experience and be highly motivated to deploy diverse strategies to extract novel findings of importance to pathophysiology. Previous research experience in an ambitious research environment is required.

Duties

The fellow will be responsible for all experimental work concerning acquisition of spatial- and cell-type resolved proteomes from heart samples, evaluation and analysis of the acquired data, formulation of hypotheses based on the data, and testing of the data in hIPSC derived cardiomyocytes. The work will be performed in collaboration with current members of the Lundby group. The fellow will work independently and lead this part of the project, with the freedom to modify the original research plan as needed. Ongoing support will be available from the PI as well as Lundby group members.

Our group and environment
The candidate will be part of the Cardiac Proteomics and Systems Biology group led by Professor Lundby at the Department of Biomedical Sciences at the University of Copenhagen, Denmark. The successful candidate will be working in a team of scientists across multiple scientific fields focused on improving our molecular understanding of cardiac pathophysiology. Our facilities include state-of-the-art laboratories and core facilities as well as modern office spaces. The position provides a unique opportunity to develop expertise in cutting edge quantitative mass spectrometry-based proteomics, data analysis of large datasets and integration of multi-omics datasets. Striving for academic excellence, collegial respect and freedom tempered by responsibility, we offer creative, friendly and stimulating working conditions in a dynamic and strong scientific environment.

Salary and terms of employment
Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 38,700 DKK/approx. 5,100 EUR (April 2025 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Workplace and period of employment
Workplace is located at Maersk Tower, The Panum Institute, University of Copenhagen, Denmark. The period of employment is 3 years, and the average weekly working hours are 37 hours per week. The starting date is 1 August 2025 or as soon as possible hereafter. 

Further information
Further information may be obtained from Professor Lundby: alicia.lundby@sund.ku.dk.

You can read more about Cardiac Proteomics Group at www.lundbylab.com

You can read more about the Department of Biomedical Sciences at www.bmi.ku.dk

Application procedure
Interested candidates are encouraged to submit an online application by clicking “APPLY NOW” below no later than May 1st, 2025, 23.59pm CET

The File Must Include

Applications must be submitted as one PDF file containing all materials to be given consideration. Attach all your materials in English in one PDF file. The application should contain:

• Application (cover letter)
• CV
• Relevant diplomas (an official translation into English). For PhD applicants: Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
• List of publications
• Contact details for two referees

Applications and enclosures received after the deadline will not be considered.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.