PhD Fellow to Division of Cell and Gene Therapy, Center for Translational Neuromedicine

Faculty of Health and Medical Sciences
University of Copenhagen

The Division of Cell and Gene Therapy of the Center for Translational Neuromedicine (CTN) is looking for a highly motivated PhD Fellow commencing 15 December 2019 or as soon as possible hereafter.

Our research team
The Center for Translational Neuromedicine is part of the Faculty of Health and Medical Sciences, University of Copenhagen, and is located in the Panum Institute. For more information, visit https://ctn.ku.dk/.

This position offers the opportunity to work in a collaborative multi-disciplinary team engaged in translational stem cell research. Our efforts are focused on understanding the role of glia in several neurological and neuropsychiatric disorders (Huntington’s disease, schizophrenia, ALS-FTD and the childhood leukodystrophies). In particular, we are interested in defining the differences in the dynamic regulation of genes and signaling pathways in glial cells, as a way to identify novel therapeutic targets and to develop cell-based therapy strategies for the treatment of some of these disorders.

In general, the Center is highly international, and thus our common language, both scientifically and socially, is English. The Center is characterized by being a newly established research unit, highly ambitious, fast-paced and hard-working. Our group has a strong collaboration with our sister lab in the US. The Division is currently composed of a Principal Investigator, 2 assistant professors, PhD students and research assistants, an animal caretaker, a bioinformatician, a lab assistant and the administration.

Project
A PhD position is available for assessing epigenetic regulation of transcription in glial cells, and its dysregulation in the neurodegenerative diseases, with a focus on Huntington disease and schizophrenia. Applicants must have strong experience in both cell biology and neurobiology, with documented experience in epigenetics. The successful candidate will have a Master’s degree and at least 2 years bench experience in molecular biology, including cloning and genetic editing, and basic bioinformatic expertise in the analysis of RNAseq, ChiPSeq and ATACseq data.

Job description

  • Carry through an independent research project under supervision
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
  • Participate in active research environments including a stay at another research team
  • Obtain experience with teaching or other types of dissemination related to your PhD project
  • Write a PhD thesis on the grounds of your project

Required skills

  • Cloning
  • Genetic editing
  • RNAseq, ChiPSeq and ATACseq data

Experience with all or as many of the techniques listed above is required. Additionally, proactivity and independence to setup and troubleshoot new protocols as new experiments are designed is expected to be taken as an attractive challenge. The ability to find a balance between learning fast and working independently, in one hand, while being able to freely ask questions when unsure about some aspects of the work is extremely important for the success of this project.

Background and qualifications

  • Candidates for the PhD position must hold a Master’s degree in neuroscience, biomedicine or other relevant field
  • At least 2 years of competent laboratory experience enabling the candidate to execute independent laboratory work
  • The successful candidate have most of the skills listed at the start of employment which means that experience in cell culture and molecular biology
  • The successful candidate is organized, self-motivated, result-oriented and capable of working independently
  • The successful candidate is highly motivated, passionate by science and driven to be part of translational efforts
  • The successful candidate will possess strong written and oral communication skills with the ability to readily learn new experimental techniques.
  • Strong analytical, communication, organizational and computer skills are also required

Employment conditions
The position is a full-time position and is open from 15 December 2019 or as soon as possible hereafter. This is a 3-year position.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around  DKK 27,360 /approx. 3,660 EUR (Oct 2019-level) plus pension.

The successful candidate will report to Steve Goldman (Principal Investigator).

The successful candidate will have to submit an application for enrollment to the SUND Graduate School for enrollment by the end of November 2019.

Further information on the Center can be found at https://ctn.ku.dk/. Inquiries about the position can be made to Professor Steven Goldman, goldman@sund.ku.dk or Administrator Ann Christensen, ann.christensen@sund.ku.dk.

Application
Your application in English must be submitted by clicking 'Apply now'.  

Application deadline is 18 November 2019 23.59pm CET .

Only online applications will be accepted and must include:  

  • Curriculum vitae – including a list of techniques that you already know
  • Cover letter including a brief project proposal as well as a clear motivation for the project
  • Copy of relevant diplomas
  • Names and contact information of 3 references, with associated letters of recommendation

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 47

The Faculty of Health and Medical Sciences comprises approximately 7800 students, 1550 PhD students and 4400 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position. 

SØG STILLINGEN

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt

Ann Lee Berger Christensen

Kontakt

Steven Alan Goldman

Info

Ansøgningsfrist: 18-11-2019
Ansættelsesdato: 15-12-2019
Arbejdstid: Fuldtid
Afdeling/Sted: Center for Translational Neuromedicine

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