Postdoc Position in Nutrient and Metabolite Sensing

Novo Nordisk Foundation Center for Basic Metabolic Research

Faculty of Health and Medical Sciences

University of Copenhagen

We are looking for a highly motivated and dynamic researcher with interest in and experience with metabolic research and pharmacological approaches to start in a 2-year postdoc position commencing on 1 November 2019.

Background

The Center was established in 2010 through a generous, unrestricted grant from the Novo Nordisk Foundation (NNF). The vision of the Center is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms of metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. The Center has around 200 employees from all over the world. We moved into new laboratories, offices and meeting rooms in the Maersk Tower in summer 2017. In 2018, the Center obtained new strategic funding from NNF to further expand and establish/develop five enabling biology and technology platforms in support of the new research strategy. You can read more about us at http://cbmr.ku.dk.

The position is in the Schwartz group. The aim of the group is to characterize and understand how signalling metabolites and their specific GPCR sensors interact with hormonal and neuronal mechanisms to control endocrine and metabolic functions as the basis for developing novel means to prevent and treat obesity and diabetes. You can read more about the Schwartz group at https://cbmr.ku.dk/research/nutrient-and-metabolite-sensing/schwartz-group/.

Project description

Key metabolites function not only as an energy sources and metabolic building blocks but also as extracellular signals of fuel availability and metabolic stress signals, which are being sensed through specific cell surface receptors, GPCRs. Most of these signalling metabolites are believed to act locally within the endocrine and metabolic tissues as autocrine and paracrine signals. The project aims at characterizing the signalling metabolite repertoire of adipose tissue and metabolite-mediated cross-talk between adipocytes and immune cells in primary cell cultures obtained from normal and obese human subjects. Cell cultures will be subjected to metabolic stress and the functional characterization will involve the use of selective pharmacological tool compounds for the metabolite receptors.

Profile

We are looking for a highly motivated and enthusiastic scientist with the following competencies and qualifications:

  • A PhD degree preferably within metabolic research and pharmacology or a related field  
  • Experience in the design, implementation and analysis of studies using pharmacological tool compounds
  • Hands on experience in working with primary human adipocytes and immune cells  
  • Advanced skills in establishing and interpreting metabolomics analysis
  • Proven track record showing scientific productivity in peer reviewed journals
  • Excellent written and oral communication skills
  • Previous teaching experience will be considered an advantage

Terms of employment

The postdoc position is a full-time position for 2 years. Starting date is 1 November 2019.
 
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
 
Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
 
The positions are covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of 28 June 28 2013.
 
Questions

For further information about the position, please contact Professor Thue Schwartz at tws@sund.ku.dk. For questions regarding the recruitment procedure, please contact SUND HR CBMR at SUND-HR-CBMR@sund.ku.dk.

International applicants may find this links useful: www.ism.ku.dk (International Staff Mobility) and https://www.workindenmark.dk/.

Application procedure

Your online application must be submitted by clicking ‘Apply now’ below. Furthermore, your application must include the following documents in PDF format: 

  • Motivated letter of application (max. one page)
  • Curriculum vitae (your ORCID must be included)
  • Full list of publications
  • References (name and contact details of at least two references)

 The application deadline is 25 September 2019 at 23.59pm CET.
 
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether an unbiased assessor has passed their application for assessment. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
 
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

SØG STILLINGEN

Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Kontakt

Thue W. Schwartz
E-mail: tws@sund.ku.dk

Info

Ansøgningsfrist: 25-09-2019
Ansættelsesdato: 01-11-2019
Arbejdstid: Fuldtid
Afdeling/Sted: Novo Nordisk Foundation Center for Basic Metabolic Research

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